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TitleA phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
Journal, issue, pagesGenes Dev., Vol. 29, Page 123-128, Year 2015
Publish dateDec 10, 2014 (structure data deposition date)
AuthorsZhang, P. / Chaturvedi, C.P. / Tremblay, V. / Cramet, M. / Brunzelle, J.S. / Skiniotis, G. / Brand, M. / Shilatifard, A. / Couture, J.F.
External linksGenes Dev. / PubMed:25593305
MethodsX-ray diffraction
Resolution2.1 - 2.2 Å
Structure data

PDB-4x8n:
Crystal structure of Ash2L SPRY domain in complex with phosphorylated RbBP5
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4x8p:
Crystal structure of Ash2L SPRY domain in complex with RbBP5
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / histone / MLL1 / chromatin / epigenetics

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