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TitleStructural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 5214-5225, Year 2015
Publish dateAug 13, 2014 (structure data deposition date)
AuthorsMori, T. / Yang, D. / Matsui, T. / Hashimoto, M. / Morita, H. / Fujii, I. / Abe, I.
External linksJ. Biol. Chem. / PubMed:25564614
MethodsX-ray diffraction
Resolution1.706 - 2.303 Å
Structure data

PDB-3wxy:
Crystal structure of CsyB complexed with CoA-SH
Method: X-RAY DIFFRACTION / Resolution: 1.706 Å

PDB-3wxz:
The structure of the I375F mutant of CsyB
Method: X-RAY DIFFRACTION / Resolution: 2.303 Å

PDB-3wy0:
The I375W mutant of CsyB complexed with CoA-SH
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

Chemicals

ChemComp-COA:
COENZYME A

ChemComp-HOH:
WATER

Source
  • aspergillus oryzae (mold)
KeywordsTRANSFERASE / CsyB / type III polyketide synthase / acyltransferase

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