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TitleVirus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Journal, issue, pagesScience, Vol. 347, Page 71-74, Year 2015
Publish dateOct 8, 2014 (structure data deposition date)
AuthorsLiu, Y. / Sheng, J. / Fokine, A. / Meng, G. / Shin, W.H. / Long, F. / Kuhn, R.J. / Kihara, D. / Rossmann, M.G.
External linksScience / PubMed:25554786
MethodsX-ray diffraction
Resolution2 - 2.32 Å
Structure data

PDB-4wm7:
Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril
Method: X-RAY DIFFRACTION / Resolution: 2.32 Å

PDB-4wm8:
Crystal Structure of Human Enterovirus D68
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-W11:
3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE / antivirus*YM

ChemComp-HOH:
WATER

ChemComp-DKA:
DECANOIC ACID

Source
  • enterovirus d68
KeywordsVIRUS / Enterovirus / Capsid / Beta jelly roll / capsid-binding inhibitor

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