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Structure paper

TitleStructural basis for misfolding in myocilin-associated glaucoma.
Journal, issue, pagesHum. Mol. Genet., Vol. 24, Page 2111-2124, Year 2015
Publish dateNov 14, 2014 (structure data deposition date)
AuthorsDonegan, R.K. / Hill, S.E. / Freeman, D.M. / Nguyen, E. / Orwig, S.D. / Turnage, K.C. / Lieberman, R.L.
External linksHum. Mol. Genet. / PubMed:25524706
MethodsX-ray diffraction
Resolution1.9 - 2.15 Å
Structure data

PDB-4wxq:
Crystal Structure of the Myocilin Olfactomedin Domain
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-4wxs:
Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4wxu:
Crystal Structure of the Selenomthionine Incorporated Myocilin Olfactomedin Domain E396D Variant.
Method: X-RAY DIFFRACTION / Resolution: 2.092 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / beta propeller / 5 bladed propeller / olfactomedin

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