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Structure paper

TitleUnique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic
Journal, issue, pagesStructure, Vol. 23, Page 56-67, Year 2015
Publish dateApr 13, 2014 (structure data deposition date)
AuthorsKottur, J. / Sharma, A. / Gore, K.R. / Narayanan, N. / Samanta, B. / Pradeepkumar, P.I. / Nair, D.T.
External linksStructure / PubMed:25497730
MethodsX-ray diffraction
Resolution2.176 - 2.71 Å
Structure data

PDB-4q43:
Polymerase-damaged DNA complex
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-4q44:
Polymerase-Damaged DNA Complex
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

PDB-4q45:
DNA Polymerase- damaged DNA complex
Method: X-RAY DIFFRACTION / Resolution: 2.176 Å

Chemicals

ChemComp-0KX:
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-1FZ:
5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine

Source
  • escherichia coli (E. coli)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / POLYMERASE / DNA POLYMERASE / TRANSLESION SYNTHESIS / TRANSFERASE-DNA COMPLEX / DNA

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