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Structure paper

TitleAnalysis of mRNA recognition by human thymidylate synthase.
Journal, issue, pagesBiosci. Rep., Vol. 34, Page e00168-e00168, Year 2014
Publish dateSep 5, 2012 (structure data deposition date)
AuthorsBrunn, N.D. / Dibrov, S.M. / Kao, M.B. / Ghassemian, M. / Hermann, T.
External linksBiosci. Rep. / PubMed:25423174
MethodsX-ray diffraction
Resolution3.005 - 3.095 Å
Structure data

PDB-4gyh:
Structure of human thymidylate synthase at high salt conditions
Method: X-RAY DIFFRACTION / Resolution: 3.005 Å

PDB-4h1i:
Structure of human thymidylate synthase at low salt conditions
Method: X-RAY DIFFRACTION / Resolution: 3.095 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Methyl transferase / nucleotide metabolism / cancer chemotherapy target

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