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Structure paper

TitleStructure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Journal, issue, pagesCell Res., Vol. 24, Page 1490-1492, Year 2014
Publish dateSep 19, 2014 (structure data deposition date)
AuthorsLi, F. / Zhao, D. / Wu, J. / Shi, Y.
External linksCell Res. / PubMed:25412658
MethodsX-ray diffraction
Resolution2.1 - 2.15 Å
Structure data

PDB-4rdn:
Structure of YTH-YTHDF2 in complex with m6A
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4rdo:
Structure of YTH-YTHDF2 in the free state
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-6MD:
N-methyladenosine

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / m6A methylated RNA binding / atypical Beta-Propeller / RNA binding / m6A methylated RNA

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