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TitleDicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
Journal, issue, pagesJ. Med. Chem., Vol. 57, Page 9933-9944, Year 2014
Publish dateAug 26, 2014 (structure data deposition date)
AuthorsChhabra, S. / Belgi, A. / Bartels, P. / van Lierop, B.J. / Robinson, S.D. / Kompella, S.N. / Hung, A. / Callaghan, B.P. / Adams, D.J. / Robinson, A.J. / Norton, R.S.
External linksJ. Med. Chem. / PubMed:25393758
MethodsNMR (solution)
Structure data

PDB-2mto:
Non-reducible analogues of alpha-conotoxin RgIA: [2,8]-cis dicarba RgIA
Method: SOLUTION NMR

PDB-2mtt:
Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-cis dicarba RgIA
Method: SOLUTION NMR

PDB-2mtu:
Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-trans dicarba RgIA
Method: SOLUTION NMR

Source
  • conus regius (invertebrata)
  • synthetic construct (others)
KeywordsTOXIN / dicarba / RgIA / Non-reducible / DE NOVO PROTEIN / alpha-conotoxin

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