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-Structure paper
Title | Design and Synthesis of Highly Potent and Isoform Selective JNK3 Inhibitors: SAR Studies on Aminopyrazole Derivatives. |
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Journal, issue, pages | J. Med. Chem., Vol. 57, Page 10013-10030, Year 2014 |
Publish date | Sep 24, 2014 (structure data deposition date) |
Authors | Zheng, K. / Iqbal, S. / Hernandez, P. / Park, H. / LoGrasso, P.V. / Feng, Y. |
External links | J. Med. Chem. / PubMed:25393557 |
Methods | X-ray diffraction |
Resolution | 1.79 Å |
Structure data | PDB-4whz: |
Chemicals | ChemComp-3NL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / JNK3 / JNK2 / JNK1 / p38 / Kinase Inhibitor / Parkinson Disease / Isoform-selectivity / Aminopyrazole / TRANSFERASE-TRANSFERASE INHIBITOR complex |