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TitleStructure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 492-504, Year 2015
Publish dateJun 27, 2014 (structure data deposition date)
AuthorsBerkut, A.A. / Peigneur, S. / Myshkin, M.Y. / Paramonov, A.S. / Lyukmanova, E.N. / Arseniev, A.S. / Grishin, E.V. / Tytgat, J. / Shenkarev, Z.O. / Vassilevski, A.A.
External linksJ. Biol. Chem. / PubMed:25352595
MethodsNMR (solution)
Structure data

PDB-2mqu:
Spatial structure of Hm-3, a membrane-active spider toxin affecting sodium channels
Method: SOLUTION NMR

Source
  • heriaeus melloteei (spider)
KeywordsTOXIN / spider toxins / voltage-gated sodium channels / gating modifiers / inhibitor cystine knot / ICK / channel activation

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