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Structure paper

TitleStructural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247.
Journal, issue, pagesFaseb J., Vol. 29, Page 70-80, Year 2015
Publish dateJul 3, 2010 (structure data deposition date)
AuthorsKirby, K.A. / Ong, Y.T. / Hachiya, A. / Laughlin, T.G. / Chiang, L.A. / Pan, Y. / Moran, J.L. / Marchand, B. / Singh, K. / Gallazzi, F. ...Kirby, K.A. / Ong, Y.T. / Hachiya, A. / Laughlin, T.G. / Chiang, L.A. / Pan, Y. / Moran, J.L. / Marchand, B. / Singh, K. / Gallazzi, F. / Quinn, T.P. / Yoshimura, K. / Murakami, T. / Matsushita, S. / Sarafianos, S.G.
External linksFaseb J. / PubMed:25351987
MethodsX-ray diffraction
Resolution1.55 Å
Structure data

PDB-3ntc:
Crystal structure of KD-247 Fab, an anti-V3 antibody that inhibits HIV-1 Entry
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / KD-247 / humanized antibody / anti-V3 / Fab

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