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TitleIdentification and characterization of amlexanox as a g protein-coupled receptor kinase 5 inhibitor.
Journal, issue, pagesMolecules, Vol. 19, Page 16937-16949, Year 2014
Publish dateSep 3, 2014 (structure data deposition date)
AuthorsHoman, K.T. / Wu, E. / Cannavo, A. / Koch, W.J. / Tesmer, J.J.
External linksMolecules / PubMed:25340299
MethodsX-ray diffraction
Resolution2.81 Å
Structure data

PDB-4wbo:
Bovine G Protein Coupled Receptor Kinase 1 in Complex with Amlexanox
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

Chemicals

ChemComp-ANW:
2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid / antiinflammatory*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / G-Protein-Coupled Receptor Kinase 1 / Amlexanox / Phosphorylation / Protein Conformation / Protein Kinase Inhibitors / TRANSFERASE-TRANSFERASE INHIBITOR complex

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