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-Structure paper
Title | Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. |
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Journal, issue, pages | J. Med. Chem., Vol. 57, Page 9598-9611, Year 2014 |
Publish date | Jun 2, 2013 (structure data deposition date) |
![]() | Spicer, T.P. / Jiang, J. / Taylor, A.B. / Choi, J.Y. / Hart, P.J. / Roush, W.R. / Fields, G.B. / Hodder, P.S. / Minond, D. |
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Methods | X-ray diffraction |
Resolution | 1.66 Å |
Structure data | ![]() PDB-4l19: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-FMT: ![]() ChemComp-1UA: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / metalloprotease / hydrolase / MMP-13 / collagenase / exosite inhibitor / HYDROLASE-HYDROLASE INHIBITOR complex |