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-Structure paper
Title | Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes. |
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Journal, issue, pages | Science, Vol. 346, Page 638-641, Year 2014 |
Publish date | May 19, 2014 (structure data deposition date) |
![]() | Baud, M.G. / Lin-Shiao, E. / Cardote, T. / Tallant, C. / Pschibul, A. / Chan, K.H. / Zengerle, M. / Garcia, J.R. / Kwan, T.T. / Ferguson, F.M. / Ciulli, A. |
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Methods | X-ray diffraction |
Resolution | 1.5 - 1.8 Å |
Structure data | ![]() PDB-4qeu: ![]() PDB-4qev: ![]() PDB-4qew: |
Chemicals | ![]() ChemComp-ACT: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-31O: ![]() ChemComp-2PE: ![]() ChemComp-NI: ![]() ChemComp-31P: |
Source |
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![]() | TRANSCRIPTION / Bromodomain-containing protein 2 / KIAA9001 / RING3 / Transcription regulation / transcription/transcription inhibitor / transcription-transcription inhibitor complex |