+Search query
-Structure paper
Title | Biased multicomponent reactions to develop novel bromodomain inhibitors. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 57, Page 9019-9027, Year 2014 |
Publish date | Sep 26, 2014 (structure data deposition date) |
![]() | McKeown, M.R. / Shaw, D.L. / Fu, H. / Liu, S. / Xu, X. / Marineau, J.J. / Huang, Y. / Zhang, X. / Buckley, D.L. / Kadam, A. ...McKeown, M.R. / Shaw, D.L. / Fu, H. / Liu, S. / Xu, X. / Marineau, J.J. / Huang, Y. / Zhang, X. / Buckley, D.L. / Kadam, A. / Zhang, Z. / Blacklow, S.C. / Qi, J. / Zhang, W. / Bradner, J.E. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.56 Å |
Structure data | ![]() PDB-4wiv: |
Chemicals | ![]() ChemComp-3P2: ![]() ChemComp-EDO: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
|
![]() | transcription/transcription inhibitor / Drug Discovery / Epigenesis / Structure-Activity Relationship / Tumor / transcription-transcription inhibitor complex |