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TitleAltered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2-Restricted T Cell Epitopes.
Journal, issue, pagesJ Immunol., Vol. 193, Page 4803-4813, Year 2014
Publish dateSep 29, 2014 (structure data deposition date)
AuthorsHoppes, R. / Oostvogels, R. / Luimstra, J.J. / Wals, K. / Toebes, M. / Bies, L. / Ekkebus, R. / Rijal, P. / Celie, P.H. / Huang, J.H. ...Hoppes, R. / Oostvogels, R. / Luimstra, J.J. / Wals, K. / Toebes, M. / Bies, L. / Ekkebus, R. / Rijal, P. / Celie, P.H. / Huang, J.H. / Emmelot, M.E. / Spaapen, R.M. / Lokhorst, H. / Schumacher, T.N. / Mutis, T. / Rodenko, B. / Ovaa, H.
External linksJ Immunol. / PubMed:25311806
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-4wj5:
Structure of HLA-A2 in complex with an altered peptide ligands based on Mart-1 variant epitope
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antigen Presentation / Major histocompatibility complex / HLA-A2 Antigen / Altered peptide ligand

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