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-Structure paper
| Title | Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA. |
|---|---|
| Journal, issue, pages | Mol. Cell, Vol. 56, Page 541-550, Year 2014 |
| Publish date | Sep 12, 2014 (structure data deposition date) |
Authors | Polikanov, Y.S. / Szal, T. / Jiang, F. / Gupta, P. / Matsuda, R. / Shiozuka, M. / Steitz, T.A. / Vazquez-Laslop, N. / Mankin, A.S. |
External links | Mol. Cell / PubMed:25306922 |
| Methods | X-ray diffraction |
| Resolution | 2.7 Å |
| Structure data | ![]() PDB-4w2i: |
| Chemicals | ![]() ChemComp-MG: ![]() ChemComp-NEG: ![]() ChemComp-SF4: ![]() ChemComp-ZN: ![]() ChemComp-K: ![]() ChemComp-HOH: |
| Source |
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Keywords | RIBOSOME/ANTIBIOTIC / Negamycin / antibiotic / 70S ribosome / inhibition of translation / miscoding / translocation inhibitor / 30S subunit with negamycin / mRNA / deacylated A- / P- / and E-site tRNAs of the 1st 70S ribosome in the ASU / Functional complex of bacterial 70S ribosome with antibiotic negamycin / 50S subunit of the 1st 70S ribosome in the ASU / RIBOSOME-ANTIBIOTIC complex |
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thermus thermophilus (bacteria)
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