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-Structure paper
Title | Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition. |
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Journal, issue, pages | J. Biol. Chem., Vol. 289, Page 33287-33295, Year 2014 |
Publish date | Aug 22, 2014 (structure data deposition date) |
Authors | Sippel, K.H. / Vyas, N.K. / Zhang, W. / Sankaran, B. / Quiocho, F.A. |
External links | J. Biol. Chem. / PubMed:25301948 |
Methods | X-ray diffraction |
Resolution | 1.7 - 1.84 Å |
Structure data | PDB-4w82: PDB-4w9n: |
Chemicals | ChemComp-CL: ChemComp-MG: ChemComp-NA: ChemComp-HOH: ChemComp-IMD: ChemComp-TCL: |
Source |
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Keywords | OXIDOREDUCTASE / fatty acid synthase / fatty acid metabolism / NADPH-dependent / enoyl reductase |