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Structure paper

TitleSubstrate-induced DNA Polymerase beta Activation.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 31411-31422, Year 2014
Publish dateAug 22, 2014 (structure data deposition date)
AuthorsBeard, W.A. / Shock, D.D. / Batra, V.K. / Prasad, R. / Wilson, S.H.
External linksJ. Biol. Chem. / PubMed:25261471
MethodsX-ray diffraction
Resolution1.85 - 2.25 Å
Structure data

PDB-4r63:
Binary complex crystal structure of R258A mutant of DNA polymerase Beta
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-4r64:
Binary complex crystal structure of E295K mutant of DNA polymerase Beta
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4r65:
Ternary complex crystal structure of R258A mutant of DNA polymerase Beta
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-4r66:
Ternary complex crystal structure of E295K mutant of DNA polymerase Beta
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-DUP:
2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTransferase/DNA / DNA Polymerase Beta / Conformational Change / enzyme mechanism / Transferase-DNA complex

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