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TitleHigh-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Journal, issue, pagesBiochemistry, Vol. 53, Page 6520-6529, Year 2014
Publish dateMay 27, 2014 (structure data deposition date)
AuthorsHe, H. / Chen, Q. / Georgiadis, M.M.
External linksBiochemistry / PubMed:25251148
MethodsX-ray diffraction
Resolution1.4 - 2.175 Å
Structure data

PDB-4qh9:
Crystal structure of Mn2+ bound human APE1
Method: X-RAY DIFFRACTION / Resolution: 2.175 Å

PDB-4qhd:
Crystal structure of apo human APE1
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-4qhe:
Crystal structure of Mg2+ bound human APE1
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsLYASE / Beta Sandwich / Endonuclease / DNA-binding / Nucleus

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