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-Structure paper
Title | Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 24, Page 4812-4817, Year 2014 |
Publish date | Aug 22, 2014 (structure data deposition date) |
Authors | Shaw, D. / Hollingworth, G. / Soldermann, N. / Sprague, E. / Schuler, W. / Vangrevelinghe, E. / Duggan, N. / Thomas, M. / Kosaka, T. / Waters, N. / van Eis, M.J. |
External links | Bioorg. Med. Chem. Lett. / PubMed:25248678 |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | PDB-4w7p: |
Chemicals | ChemComp-3J7: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / inhibitor / kinase / TRANSFERASE-TRANSFERASE INHIBITOR complex |