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Title | X-ray crystallographic analysis of IMP-1 metallo-beta-lactamase complexed with a 3-aminophthalic acid derivative, structure-based drug design, and synthesis of 3,6-disubstituted phthalic acid derivative inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 24, Page 4891-4894, Year 2014 |
Publish date | Jul 29, 2014 (structure data deposition date) |
![]() | Hiraiwa, Y. / Saito, J. / Watanabe, T. / Yamada, M. / Morinaka, A. / Fukushima, T. / Kudo, T. |
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Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-3wxc: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-C93: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / lactamase / HYDROLASE-HYDROLASE INHIBITOR complex |