+Search query
-Structure paper
Title | Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water. |
---|---|
Journal, issue, pages | Bioorg. Chem., Vol. 57, Page 242-, Year 2014 |
Publish date | May 16, 2014 (structure data deposition date) |
Authors | Heyes, L.C. / Reichau, S. / Cross, P.J. / Jameson, G.B. / Parker, E.J. |
External links | Bioorg. Chem. / PubMed:25245459 |
Methods | X-ray diffraction |
Resolution | 1.76 - 2.34 Å |
Structure data | PDB-4uma: PDB-4umb: PDB-4umc: |
Chemicals | ChemComp-MN: ChemComp-GZ3: ChemComp-HOH: ChemComp-PO4: ChemComp-0V5: ChemComp-PEQ: |
Source |
|
Keywords | TRANSFERASE / DAH7PS / DAHPS / AROMATIC AMINO ACIDS / SHIKIMATE PATHWAY / OXOCARBENIUM ION / ENZYME INHIBITORS / MENINGITIS |