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TitleIRAK4 Dimerization and trans-Autophosphorylation Are Induced by Myddosome Assembly.
Journal, issue, pagesMol. Cell, Vol. 55, Page 891-903, Year 2014
Publish dateAug 5, 2014 (structure data deposition date)
AuthorsFerrao, R. / Zhou, H. / Shan, Y. / Liu, Q. / Li, Q. / Shaw, D.E. / Li, X. / Wu, H.
External linksMol. Cell / PubMed:25201411
MethodsX-ray diffraction
Resolution2.65 - 2.8 Å
Structure data

PDB-4u97:
Crystal Structure of Asymmetric IRAK4 Dimer
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-4u9a:
Sulphur Anomalous Crystal Structure of Asymmetric IRAK4 Dimer
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-STU:
STAUROSPORINE / anticancer, antifungal, antibiotic, alkaloid*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase / Autophosphorylation / Dimer / Sulphur Anomalous

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