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Structure paper

TitleStructure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 21, Page 864-870, Year 2014
Publish dateMay 12, 2014 (structure data deposition date)
AuthorsHara, K. / Zheng, G. / Qu, Q. / Liu, H. / Ouyang, Z. / Chen, Z. / Tomchick, D.R. / Yu, H.
External linksNat. Struct. Mol. Biol. / PubMed:25173175
MethodsX-ray diffraction
Resolution2.85 - 3.05 Å
Structure data

PDB-4pju:
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1)
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-4pjw:
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-4pk7:
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / Sister chromatid cohesion / cohesin subunits / protein-protein interaction / HEAT repeat

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