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TitleHIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization.
Journal, issue, pagesPlos Pathog., Vol. 10, Page e1004337-e1004337, Year 2014
Publish dateApr 10, 2014 (structure data deposition date)
AuthorsNavis, M. / Tran, K. / Bale, S. / Phad, G.E. / Guenaga, J. / Wilson, R. / Soldemo, M. / McKee, K. / Sundling, C. / Mascola, J. ...Navis, M. / Tran, K. / Bale, S. / Phad, G.E. / Guenaga, J. / Wilson, R. / Soldemo, M. / McKee, K. / Sundling, C. / Mascola, J. / Li, Y. / Wyatt, R.T. / Karlsson Hedestam, G.B.
External linksPlos Pathog. / PubMed:25166308
MethodsX-ray diffraction
Resolution1.93 Å
Structure data

PDB-4q2z:
Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • macaca mulatta (Rhesus monkey)
KeywordsIMMUNE SYSTEM / Fab fragment / HIV viral envelope glycoprotein neutralization

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