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TitleOxygenase-catalyzed desymmetrization of N,N-dialkyl-piperidine-4-carboxylic acids.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 53, Page 10925-10927, Year 2014
Publish dateApr 2, 2014 (structure data deposition date)
AuthorsRydzik, A.M. / Leung, I.K. / Kochan, G.T. / McDonough, M.A. / Claridge, T.D. / Schofield, C.J.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:25164544
MethodsX-ray diffraction
Resolution1.899 Å
Structure data

PDB-4cwd:
CRYSTAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE,2-OXOGLUTARATE IN COMPLEX WITH 449, A NOVEL SUBSTRATE
Method: X-RAY DIFFRACTION / Resolution: 1.899 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-ZN:
Unknown entry

ChemComp-449:
4-carboxy-1,1-dimethylpiperidin-1-ium

ChemComp-OGA:
N-OXALYLGLYCINE / inhibitor*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / 2-OG AND IRON DEPENDENT DIOXYGENASE / CARNITINE BIOSYNTHESIS

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