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TitleFormation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 27513-, Year 2014
Publish dateMay 30, 2014 (structure data deposition date)
AuthorsBrumshtein, B. / Esswein, S.R. / Landau, M. / Ryan, C.M. / Whitelegge, J.P. / Phillips, M.L. / Cascio, D. / Sawaya, M.R. / Eisenberg, D.S.
External linksJ. Biol. Chem. / PubMed:25138218
MethodsX-ray diffraction
Resolution0.95 - 2.7 Å
Structure data

PDB-4unt:
Induced monomer of the Mcg variable domain
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4unu:
MCG - a dimer of lambda variable domains
Method: X-RAY DIFFRACTION / Resolution: 0.95 Å

PDB-4unv:
Covalent dimer of lambda variable domains
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-15P:
POLYETHYLENE GLYCOL (N=34) / precipitant*YM

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / BENCE-JONES / LIGHT CHAINS / IMMUNOGLOBULIN / AMYLOID

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