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-Structure paper
タイトル | Investigating the Contribution of the Active Site Environment to the Slow Reaction of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 with Oxygen. |
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ジャーナル・号・ページ | Biochem. J., Vol. 463, Page 363-, Year 2014 |
掲載日 | 2014年8月11日 (構造データの登録日) |
![]() | Tarhonskaya, H. / Chowdhury, R. / Leung, I.K.H. / Loik, N.D. / Mccullagh, J.S.O. / Claridge, T.D.W. / Schofield, C.J. / Flashman, E. |
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手法 | X線回折 |
解像度 | 1.721 Å |
構造データ | ![]() PDB-4uwd: |
化合物 | ![]() ChemComp-MN: ![]() ChemComp-UN9: ![]() ChemComp-HOH: |
由来 |
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![]() | OXIDOREDUCTASE / NON-HEME / IRON / 2-OXOGLUTARATE / DIOXYGENASE / HYPOXIA-INDUCIBLE FACTOR / HIF / HIF PROLYL HYDROXYLASE DOMAIN 2 / PHD2 / EGLN / OXYGENASE / HYPOXIA / DNA-BINDING / METAL-BINDING / TRANSCRIPTION / HELIX-LOOP-HELIX-BETA / DSBH / FACIAL TRIAD / ASPARAGINYL/ ASPARTYL HYDROXYLASE / TRANSCRIPTION AND EPIGENETIC REGULATION / SIGNALING / DEVELOPMENT / CELL STRUCTURE / ANKYRIN REPEAT DOMAIN / ARD / BETA-HYDROXYLATION / TRANSCRIPTION ACTIVATOR/INHIBITOR / PHOSPHORYLATION / S-NITROSYLATION |