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TitleCaffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis.
Journal, issue, pagesCancer Prev Res (Phila), Vol. 7, Page 1056-1066, Year 2014
Publish dateOct 2, 2013 (structure data deposition date)
AuthorsYang, G. / Fu, Y. / Malakhova, M. / Kurinov, I. / Zhu, F. / Yao, K. / Li, H. / Chen, H. / Li, W. / Lim, D.Y. ...Yang, G. / Fu, Y. / Malakhova, M. / Kurinov, I. / Zhu, F. / Yao, K. / Li, H. / Chen, H. / Li, W. / Lim, D.Y. / Sheng, Y. / Bode, A.M. / Dong, Z.
External linksCancer Prev Res (Phila) / PubMed:25104643
MethodsX-ray diffraction
Resolution1.7992 Å
Structure data

PDB-4n0s:
Complex of ERK2 with caffeic acid
Method: X-RAY DIFFRACTION / Resolution: 1.7992 Å

Chemicals

ChemComp-DHC:
CAFFEIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / caffeic acid complex / mitogen-activated protein kinase / signal-regulated kinase

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