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Structure paper

TitleA Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 24475-24487, Year 2014
Publish dateApr 9, 2014 (structure data deposition date)
AuthorsKaya, A.I. / Lokits, A.D. / Gilbert, J.A. / Iverson, T.M. / Meiler, J. / Hamm, H.E.
External linksJ. Biol. Chem. / PubMed:25037222
MethodsX-ray diffraction
Resolution2 - 2.4 Å
Structure data

PDB-4pam:
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Method: X-RAY DIFFRACTION / Resolution: 2.101 Å

PDB-4pan:
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-4pao:
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Method: X-RAY DIFFRACTION / Resolution: 2.003 Å

PDB-4paq:
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-SO3:
SULFITE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GSP:
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE

ChemComp-MG:
Unknown entry

Source
  • rattus norvegicus (Norway rat)
KeywordsSIGNALING PROTEIN / Activation of Heterotrimeric G protein / GDP release / Computer modeling / G protein Coupled Receptors / Rhodopsin / Activation of Heterotrimeric G protein GDP release

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