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TitleThe ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 21, Page 679-685, Year 2014
Publish dateMay 31, 2014 (structure data deposition date)
AuthorsTan, D. / Zhou, M. / Kiledjian, M. / Tong, L.
External linksNat. Struct. Mol. Biol. / PubMed:25026078
MethodsX-ray diffraction
Resolution1.9 - 2.9 Å
Structure data

PDB-4qik:
Crystal structure of the ROQ domain of human Roquin in complex with the TNF23 RNA duplex
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4qil:
Crystal structure of the ROQ domain of human Roquin in complex with the Hmg19 stem-loop RNA
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN/RNA / RNA duplex / Winged-helix motif / mRNA secondary structure / mRNA decay / immune responses / autoimmunity / RNA BINDING PROTEIN-RNA complex / mRNA stem-loop

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