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TitleStructural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 21, Page 671-678, Year 2014
Publish dateMay 30, 2014 (structure data deposition date)
AuthorsSchlundt, A. / Heinz, G.A. / Janowski, R. / Geerlof, A. / Stehle, R. / Heissmeyer, V. / Niessing, D. / Sattler, M.
External linksNat. Struct. Mol. Biol. / PubMed:25026077
MethodsX-ray diffraction
Resolution1.94 - 3 Å
Structure data

PDB-4qi0:
X-ray structure of the ROQ domain from murine Roquin-1
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-4qi2:
X-ray structure of the ROQ domain from murine Roquin-1 in complex with a 23-mer Tnf-CDE RNA
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsRNA BINDING PROTEIN / ROQ domain / winged-helix domain / RNA binding / Tnf CDE RNA / RNA BINDING PROTEIN/RNA / RNA BINDING PROTEIN-RNA complex

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