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TitleStructural basis for HTLV-1 protease inhibition by the HIV-1 protease inhibitor indinavir.
Journal, issue, pagesJ. Med. Chem., Vol. 57, Page 6266-6272, Year 2014
Publish dateMar 14, 2014 (structure data deposition date)
AuthorsKuhnert, M. / Steuber, H. / Diederich, W.E.
External linksJ. Med. Chem. / PubMed:25006983
MethodsX-ray diffraction
Resolution2.404 Å
Structure data

PDB-3wsj:
HTLV-1 protease in complex with the HIV-1 protease inhibitor Indinavir
Method: X-RAY DIFFRACTION / Resolution: 2.404 Å

Chemicals

ChemComp-MK1:
N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY / antivirus, antiretroviral, protease inhibitor, medication*YM

ChemComp-SO4:
SULFATE ION

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • human t-lymphotropic virus 1
KeywordsHYDROLASE/HYDROLASE INHIBITOR / retroviral protease / HYDROLASE-HYDROLASE INHIBITOR complex

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