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TitleDiscrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page 10690-10695, Year 2014
Publish dateApr 2, 2014 (structure data deposition date)
AuthorsDeng, L. / Ma, L. / Virata-Theimer, M.L. / Zhong, L. / Yan, H. / Zhao, Z. / Struble, E. / Feinstone, S. / Alter, H. / Zhang, P.
External linksProc. Natl. Acad. Sci. USA / PubMed:25002515
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-4q0x:
Crystal structure of non-neutralizing antibody in complex with Epitope II of HCV E2
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • hepatitis c virus
KeywordsIMMUNE SYSTEM/VIRAL PROTEIN / antibody / anti-HCV E2 / HCV E2 / IMMUNE SYSTEM-VIRAL PROTEIN complex

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