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| Title | SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies. |
|---|---|
| Journal, issue, pages | Clin. Cancer Res., Vol. 20, Page 4574-4583, Year 2014 |
| Publish date | Jan 15, 2014 (structure data deposition date) |
Authors | Deckert, J. / Wetzel, M.C. / Bartle, L.M. / Skaletskaya, A. / Goldmacher, V.S. / Vallee, F. / Zhou-Liu, Q. / Ferrari, P. / Pouzieux, S. / Lahoute, C. ...Deckert, J. / Wetzel, M.C. / Bartle, L.M. / Skaletskaya, A. / Goldmacher, V.S. / Vallee, F. / Zhou-Liu, Q. / Ferrari, P. / Pouzieux, S. / Lahoute, C. / Dumontet, C. / Plesa, A. / Chiron, M. / Lejeune, P. / Chittenden, T. / Park, P.U. / Blanc, V. |
External links | Clin. Cancer Res. / PubMed:24987056 |
| Methods | X-ray diffraction |
| Resolution | 1.53 Å |
| Structure data | ![]() PDB-4cmh: |
| Chemicals | ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE/IMMUNE SYSTEM / HYDROLASE-IMMUNE SYSTEM COMPLEX / MULTIPLE MYELOMA |
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homo sapiens (human)
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