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TitleAffinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page 10275-10280, Year 2014
Publish dateMay 28, 2014 (structure data deposition date)
AuthorsFera, D. / Schmidt, A.G. / Haynes, B.F. / Gao, F. / Liao, H.X. / Kepler, T.B. / Harrison, S.C.
External linksProc. Natl. Acad. Sci. USA / PubMed:24982157
MethodsX-ray diffraction
Resolution3 - 3.487 Å
Structure data

PDB-4qhk:
UCA (unbound) from CH103 Lineage
Method: X-RAY DIFFRACTION / Resolution: 3.487 Å

PDB-4qhl:
I3.2 (unbound) from CH103 Lineage
Method: X-RAY DIFFRACTION / Resolution: 3.153 Å

PDB-4qhm:
I3.1 (unbound) from CH103 Lineage
Method: X-RAY DIFFRACTION / Resolution: 3.23 Å

PDB-4qhn:
I2 (unbound) from CH103 Lineage
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fab fragment / HIV-1 / antibody

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