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Structure paper

TitleModular riboswitch toolsets for synthetic genetic control in diverse bacterial species.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 136, Page 10615-10624, Year 2014
Publish dateJul 29, 2013 (structure data deposition date)
AuthorsRobinson, C.J. / Vincent, H.A. / Wu, M.C. / Lowe, P.T. / Dunstan, M.S. / Leys, D. / Micklefield, J.
External linksJ. Am. Chem. Soc. / PubMed:24971878
MethodsX-ray diffraction
Resolution2.13 - 2.15 Å
Structure data

PDB-4lx5:
X-ray crystal structure of the M6" riboswitch aptamer bound to pyrimido[4,5-d]pyrimidine-2,4-diamine (PPDA)
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

PDB-4lx6:
X-ray crystal structure of the M6C" riboswitch aptamer bound to 2-aminopyrimido[4,5-d]pyrimidin-4(3H)-one (PPAO)
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-29G:
pyrimido[4,5-d]pyrimidine-2,4-diamine

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-29H:
2-aminopyrimido[4,5-d]pyrimidin-4(3H)-one

Source
  • vibrio vulnificus (bacteria)
KeywordsRNA / Riboswitch / Gene expression platform / Riboswitch Gene expression platform

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