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-Structure paper
Title | Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 111, Page E2530-E2539, Year 2014 |
Publish date | Feb 23, 2014 (structure data deposition date) |
Authors | Liu, Y.L. / Lindert, S. / Zhu, W. / Wang, K. / McCammon, J.A. / Oldfield, E. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:24927548 |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.5 Å |
Structure data | PDB-4p0v: PDB-4p0w: PDB-4p0x: |
Chemicals | ChemComp-ZOL: ChemComp-1WO: ChemComp-MG: ChemComp-HOH: ChemComp-1XH: |
Source |
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Keywords | transferase/transferase inhibitor / Human / FPPS / Inhibitor / Complex / Synthase / transferase-transferase inhibitor complex / TRANSFERASE / Prenyl Synthase |