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Structure paper

TitleStructural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor.
Journal, issue, pagesBiochemistry, Vol. 53, Page 4204-, Year 2014
Publish dateJun 23, 2013 (structure data deposition date)
AuthorsFerreira, P. / Villanueva, R. / Martinez-Julvez, M. / Herguedas, B. / Marcuello, C. / Fernandez-Silva, P. / Cabon, L. / Hermoso, J.A. / Lostao, A. / Susin, S.A. / Medina, M.
External linksBiochemistry / PubMed:24914854
MethodsX-ray diffraction
Resolution1.8 - 2.88 Å
Structure data

PDB-4bur:
Crystal structure of the reduced human Apoptosis inducing factor complexed with NAD
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

PDB-4bv6:
Refined crystal structure of the human Apoptosis inducing factor
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / APOPTOSIS / MITOCHONDRIA / NUCLEAR CHROMATINOLYSIS / DNA-BINDING / FLAVOPROTEIN / DNA BINDING

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