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Structure paper

TitleAzaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195.
Journal, issue, pagesACS Med Chem Lett, Vol. 4, Page 211-215, Year 2013
Publish dateJan 10, 2013 (structure data deposition date)
AuthorsTong, Y. / Stewart, K.D. / Florjancic, A.S. / Harlan, J.E. / Merta, P.J. / Przytulinska, M. / Soni, N. / Swinger, K.K. / Zhu, H. / Johnson, E.F. ...Tong, Y. / Stewart, K.D. / Florjancic, A.S. / Harlan, J.E. / Merta, P.J. / Przytulinska, M. / Soni, N. / Swinger, K.K. / Zhu, H. / Johnson, E.F. / Shoemaker, A.R. / Penning, T.D.
External linksACS Med Chem Lett / PubMed:24900653
MethodsX-ray diffraction
Resolution3.12 Å
Structure data

PDB-4iq6:
Gsk-3beta with inhibitor 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine
Method: X-RAY DIFFRACTION / Resolution: 3.12 Å

Chemicals

ChemComp-IQ6:
6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine

Source
  • homo sapiens (human)
KeywordsTransferase/Transferase Inhibitor / protein kinase / Transferase-Transferase Inhibitor complex

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