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TitleClick Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA.
Journal, issue, pagesAcs Chem. Biol., Vol. 9, Page 1780-1787, Year 2014
Publish dateOct 31, 2013 (structure data deposition date)
AuthorsPhelps, K.J. / Ibarra-Soza, J.M. / Tran, K. / Fisher, A.J. / Beal, P.A.
External linksAcs Chem. Biol. / PubMed:24896732
MethodsX-ray diffraction
Resolution1.7 - 1.96 Å
Structure data

PDB-4nfo:
Crystal Structure Analysis of the 16mer GCAGACUUAAGUCUGC
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-4nfp:
Crystal Structure Analysis of the 16mer GCAGNCUUAAGUCUGC containing 8-aza-7-deaza-7-ethynyl Adenosine
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-4nfq:
Crystal Structure Analysis of the 16mer GCAGNCUUAAGUCUGC containing 7-triazolyl-8-aza-7-deazaadenosine
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SPM:
SPERMINE

ChemComp-HOH:
WATER

ChemComp-ARF:
FORMAMIDE

KeywordsRNA / RNA 16mer oligo / 8-aza-7-deaza-7-ethynyladenosine / Position 5 / 7-triazolyl-8-aza-7-deazaadenosine

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