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TitleA mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 22205-22220, Year 2014
Publish dateApr 3, 2014 (structure data deposition date)
AuthorsAkimoto, M. / Zhang, Z. / Boulton, S. / Selvaratnam, R. / VanSchouwen, B. / Gloyd, M. / Accili, E.A. / Lange, O.F. / Melacini, G.
External linksJ. Biol. Chem. / PubMed:24878962
MethodsNMR (solution)
Structure data

PDB-2mng:
Apo Structure of human HCN4 CNBD solved by NMR
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Cyclic AMP binding domain / CS-ROSETTA

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