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TitleThe DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 21, Page 535-543, Year 2014
Publish dateSep 25, 2013 (structure data deposition date)
AuthorsFollis, A.V. / Llambi, F. / Ou, L. / Baran, K. / Green, D.R. / Kriwacki, R.W.
External linksNat. Struct. Mol. Biol. / PubMed:24814347
MethodsNMR (solution)
Structure data

PDB-2me8:
Solution Structure of BCL-xL in its p53-bound conformation determined with selective isotope labelling of I,L,V sidechains
Method: SOLUTION NMR

PDB-2me9:
Solution structure of BCL-xL containing the alpha1-alpha2 disordered loop determined with selective isotope labelling of I,L,V sidechains
Method: SOLUTION NMR

PDB-2mej:
Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / BCL-xL / p53 / BCL-2 family / cytoplasmic p53 / selective labeling

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