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TitleAmides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs.
Journal, issue, pagesNucleic Acids Res., Vol. 42, Page 6542-6551, Year 2014
Publish dateDec 18, 2013 (structure data deposition date)
AuthorsMutisya, D. / Selvam, C. / Lunstad, B.D. / Pallan, P.S. / Haas, A. / Leake, D. / Egli, M. / Rozners, E.
External linksNucleic Acids Res. / PubMed:24813446
MethodsX-ray diffraction
Resolution1.2 Å
Structure data

PDB-4o41:
Amide linked RNA
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-SR:
STRONTIUM ION

ChemComp-HOH:
WATER

KeywordsRNA / Modified RNA / RNA structure / amide RNA / amide internucleoside linkage / modified nucleoside

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