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Structure paper

TitleCancer-relevant splicing factor CAPER alpha engages the essential splicing factor SF3b155 in a specific ternary complex.
Journal, issue, pagesJ. Biol. Chem., Vol. 289, Page 17325-17337, Year 2014
Publish dateFeb 13, 2014 (structure data deposition date)
AuthorsLoerch, S. / Maucuer, A. / Manceau, V. / Green, M.R. / Kielkopf, C.L.
External linksJ. Biol. Chem. / PubMed:24795046
MethodsX-ray diffraction
Resolution1.74 - 2.2 Å
Structure data

PDB-4oz0:
Crystal structure of human CAPERalpha U2AF homology motif (apo-state)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4oz1:
Crystal structure of human CAPERalpha UHM bound to SF3b155 ULM5
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

ChemComp-LYS:
LYSINE

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / U2AF homology motif / UHM / protein-peptide complex / pre-mRNA splicing factor

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