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Structure paper

TitleThe malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Journal, issue, pagesNat Commun, Vol. 5, Page 3726-3726, Year 2014
Publish dateJul 26, 2013 (structure data deposition date)
AuthorsWithers-Martinez, C. / Strath, M. / Hackett, F. / Haire, L.F. / Howell, S.A. / Walker, P.A. / Evangelos, C. / Dodson, G.G. / Blackman, M.J.
External linksNat Commun / PubMed:24785947
MethodsX-ray diffraction
Resolution2.25 - 2.26 Å
Structure data

PDB-4lvn:
Crystal structure of PfSUB1-prodomain-NIMP.M7 Fab complex
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-4lvo:
Crystal structure of PfSUB1-prodomain-NIMP.M7 Fab complex with added CaCl2
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • mus musculus (house mouse)
Keywordshydrolase/inhibitor/immune system / alpha beta / enzyme-prodomain complex / Rossmann fold / serine protease / calcium ions / prodomain / parasitophorous vacuole / hydrolase-inhibitor-immune system complex

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