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-Structure paper
Title | In Vitro Resistance Selections for Plasmodium Falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-Binding Site and Altered Growth. |
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Journal, issue, pages | J. Biol. Chem., Vol. 289, Page 17980-, Year 2014 |
Publish date | Feb 12, 2014 (structure data deposition date) |
Authors | Ross, L.S. / Javier Gamo, F. / Lafuente-Monasterio, M.J.E. / Singh, O.M.P. / Rowland, P. / Wiegand, R.C. / Wirth, D.F. |
External links | J. Biol. Chem. / PubMed:24782313 |
Methods | X-ray diffraction |
Resolution | 1.98 - 2.82 Å |
Structure data | PDB-4cq8: PDB-4cq9: PDB-4cqa: |
Chemicals | ChemComp-FMN: ChemComp-ORO: ChemComp-JBW: ChemComp-HOH: ChemComp-XBL: ChemComp-ID6: |
Source |
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Keywords | OXIDOREDUCTASE / DHODH |