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Structure paper

TitleStructure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy.
Journal, issue, pagesJ. Pharmacol. Exp. Ther., Vol. 350, Page 110-123, Year 2014
Publish dateFeb 10, 2014 (structure data deposition date)
AuthorsPepinsky, R.B. / Arndt, J.W. / Quan, C. / Gao, Y. / Quintero-Monzon, O. / Lee, X. / Mi, S.
External linksJ. Pharmacol. Exp. Ther. / PubMed:24756303
MethodsX-ray diffraction
Resolution3.23 Å
Structure data

PDB-4oqt:
LINGO-1/Li81 Fab complex
Method: X-RAY DIFFRACTION / Resolution: 3.23 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN/IMMUNE SYSTEM / Leucine rich repeat / Ig domain / MEMBRANE PROTEIN-IMMUNE SYSTEM complex

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