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Structure paper

TitleStructure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 111, Page 6281-6286, Year 2014
Publish dateJul 30, 2013 (structure data deposition date)
AuthorsParthier, C. / Stelter, M. / Ursel, C. / Fandrich, U. / Lilie, H. / Breithaupt, C. / Stubbs, M.T.
External linksProc. Natl. Acad. Sci. USA / PubMed:24733933
MethodsX-ray diffraction
Resolution2.2 - 3.3 Å
Structure data

PDB-4lxr:
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4lxs:
Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form)
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • drosophila melanogaster (fruit fly)
KeywordsIMMUNE SYSTEM/CYTOKINE / TLR / LEUCINE-RICH REPEAT / IMMUNE SYSTEM / CYTOKINE RECEPTOR / EMBRYONIC DEVELOPMENT / INNATE IMMUNITY / RECEPTOR-LIGAND COMPLEX' / IMMUNE SYSTEM-CYTOKINE complex / RECEPTOR-LIGAND COMPLEX

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